Funded by the Gravitation Programme with 21.9 M€, the Dutch Brain Interfaces Initiative (DBI2) project thrives to bring forward the closed-loop interaction with the brain. The project investigates brain-brain interaction, brain-environment interaction, social brain interactions and networks of brains. The research is carried out by a consortium comprising five Dutch research universities, two medical centers, and one institute of the Royal Netherlands Academy of Arts and Sciences. The research topics comprise neuroscientific challenges, hardware- and computational challenges. Our lab contributes mainly to the latter ones.